Defrag will have the following speakers at the conference (more to be added):

Jon Aizen, Dapper
Bradley Allen, CTO, Siderean Software, Inc.
James Altucher, Stockpickr and Forumula Capital
Charles Armstrong, CEO, Trampoline Systems
Michael Barrett, CISO, PayPal
Jeff Clavier, SoftTech
Esther Dyson, EDventure
Brad Feld, Foundry Group and Mobius Venture Capital
Dawn Foster, Jive Software
Aaron Fulkerson, Mindtouch
Adam Gross, salesforce.com
Dick Hardt, CEO, Sxip Identity
Marti Hearst, UC-Berkeley and the Flamenco search project
JC Herz
Bradley Horowitz, VP, Product Strategy
Matthey Hurst, Scientist, Microsoft Live Labs
Alex Iskold, Founder/CEO, adaptiveblue.com
Paul Kedrosky, Infectious Greed
Steve Larsen, CEO, Krugle
Jeremy Liew, Lightspeed Venture Partners
Ross Mayfield, CEO, Socialtext
Andrew McAfee, Harvard Business School
Jerry Michalski, Sociate
Jeremie Miller, Search Wikia
Jeff Nolan, Newsgator
Brian Oberkirch, Like it matters
Lou Paglia, Director & GM, Factiva/Dow Jones
JP Rangaswami, CIO of BT Global Services
Joshua Schachter, Yahoo!
Karen Schneider, Free Range LIbrarian
Doc Searls
Eran Shir, Dapper
Clay Shirky
David Weinberger, Author of Everything is Miscellaneous
Tim Wolters, CTO, Collective Intellect